Research activities in the Department

In the Department of Radiation Oncology clinical trials and experimental research projects are conducted.

The affiliated laboratory for translational Radiation Oncology studies the biological basics and molecular mechanisms of different cancer types.

The interdisciplinary high frequency research group works on preclinical characterization and optimization of high frequency electromagnetic fields for therapeutical use.

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Research in Radiation Oncology

The Department of Radiation Oncology sets a high value in the findings of Radiation Oncology research activities:

  1. The Department initiates novel and participates in external national and international clinical trials. Phase-I and Phase-II trials are also conducted.  
  2. The laboratory for Radiobiology and translational Radiation Oncology works on molecular characterization of tumors of the head and neck region with special emphasis on detailed analysis of molecular mechanisms and cellular pathways determining the course of disease and response to radiotherapy, chemoradiation or EGFR-antibody therapy.
  3. Our interdisciplinary high frequency research group works on preclinical characterization and optimization of high frequency electromagnetic fields for therapeutical use. The results of preclinical-biological research together with planning calculations and modeling promote improvement of applications and development of novel high frequency-based therapeutic devices and facilitate and accompany their clinical implementation.

Research focus of the Radiobiology laboratory and respective contact persons

  • Radio- und chemosensitivity (Prof. Dr. Ingeborg Tinhofer-Keilholz / Dr. Diana Braunholz)
  • Liquid biopsy (Prof. Dr. Ingeborg Tinhofer-Keilholz / Stephanie Staudte / Oliver Beyer / Dr. Diana Braunholz)
  • MicroRNAs and exosomes as biomarker (Prof. Dr. Ingeborg Tinhofer-Keilholz)
  • Biomarker analysis within clinical trials (Prof. Dr. Ingeborg Tinhofer-Keilholz)
  • Next-generation sequencing - NGS (Prof. Dr. Ingeborg Tinhofer-Keilholz)
  • New:  3D cell culture (Dr. Diana Braunholz / Anna Happe-Kramer)